Sharon Kleyne Monitoring Human Testing of New Dry Eye Drug

Water Advocate Kleyne Says Jury Still Out on Lacripep. Nature’s Tears® EyeMist® Still the Surest Way To Soothe Dry Eye Symptoms.

Dry eye disease is a major affliction and the process of treating it has created a 100 billion dollar business (annually). In the U.S., dry eye affects between 5% and 9% of the total population; that number increases to 35% among older women. Dry eye disease can occur due to hormonal imbalances, malfunctioning aqueous tear production or lipid production and general inflammation of the eye. Specific symptoms include redness, swelling, soreness, itching, headache and blurred vision.

Sharon Kleyne, founder of Bio-Logic Aqua® Research Water Life Science®, is a leading expert researcher and educator of the causes and relief of dry eye, and so she is paying close attention to the development and testing of a new drug. Lacripep is a topical eye drop developed by researchers at the University of Virginia Health System and was cleared for human testing in March 2017.

According to its creators, Lacripep is a topical eye drop with difference. Rather than masking dry eye symptoms, Lacripep aims to eliminate inflammatory triggers. If successful, it will do so by restoring the natural basal tearing mechanism and the health of cells. That’s not all. Lacripep may also restore the nerves on the cornea. These are the nerves that signal the brain to create more tears. Lacripep also may stabilize the eye’s tear film, which is naturally 99 percent water. In dry eye conditions, the tear film dries out from excessive evaporation.

Research specialist Gordon Laurie of the UVA School of Medicine’s Department of Cell Biology, says that “most ophthalmic drugs are washed away right away, but that’s not the case here. Lacripep is still in the tears 24 hours later because it goes into the lipid layer and apparently comes out of the lipid layer slowly to treat the eye.” According to Laurie, the root cause of the disease is a shortage of the tear protein lacritin. Lacripep is a short synthetic fragment of lacritin. If successful, Lacripep would be the first drug to treat that cause of dry eye.

“We think that dry eye disease may be much simpler than people have thought in the past, sort of like insulin and type I diabetes,” Laurie said. “With lacritin deficient in dry eye tears, topical Lacripep is a replacement therapy, which will probably not cure the disease. You would still have to keep treating your eyes, but maybe just once a day.”

Kleyne, also the host of the nationally syndicated The Sharon Kleyne Hour Power of Water, Global Climate Change and Your Health on VoiceAmerica sponsored by Nature’s Tears® EyeMist®, awaits the results of the tests with interest. Until then, she continues to urge people suffering from dry eye disease to use Nature’s Tears® EyeMist® for relief. Nature’s Tears® EyeMist® contains no chemicals and consists of 100 percent pure Trade Secret tissue culture grade water. The product is applied as a patented micron-size mist that supplements and replenishes the tear film from a personal, portable hand-held humidifier. Most eye drops trap moisture but do not replenish it.

Nature’s Tears® EyeMist® is still the dry eye solution of choice. Millions of dry eye sufferers around the world attest to that.


Were you aware of this new water technology? Have you always used eye drops in the past? What do you think of new water research and new technology? Have you ever tried Nature’s Tears® EyeMist® or known someone who has done so? What’s the verdict?

If you have comments or stories you’d like to share, why not get involved? We’d like very much to hear from you! You can reach us in the following ways. 800-367-6478 ~ Fax 541-474-2123 or on Twitter at @sharonkleynehr


Sharon Kleyne Offers Reminder About Educational Tear Film DVD

Tear Film DVD Offers Clear Illustrations of New Water Technology. Dr. Philip Paden Hosts Tear Film DVD by Bio-Logic Aqua® Water Life Science®.

For more than two decades, Sharon Kleyne, founder of Bio-Logic Aqua® Research Water Life Science® and host of the nationally syndicated The Sharon Kleyne Hour Power of Water, Global Climate Change and Your Health on VoiceAmerica sponsored by Nature’s Tears® EyeMist®, has been teaching everyone around the world that the eye’s tear film is 99% water in its natural state. She also teaches that the eye, like the rest of the human body, begins to evaporate the moment the body leaves the mother’s watery womb. As a result, a human’s eyes and body require supplementation of fresh water or the human being will completely dehydrate and die.

A teaching aid in this quest for eye and body health is the revised edition of Bio-Logic Aqua® Research Water Life Science’s® educational DVD, The Human Tear Film – Mist Versus Eye Drops. The original film, produced by Kleyne and her company in 2001, has been widely used as an educational tool in medical schools, optometry programs, continuing education courses and other vision care programs. The DVD illustrates in animation what happens to the tear film when hit by a large eye drop. The DVD also shows how mist water droplets are able to penetrate and be absorbed by the tear film. The DVD is hosted by Medford Ophthalmologist Dr. Philip Paden, Director and owner of the Paden Eye Care Clinic. In the DVD’s current edition, animation segments are completely revised to make the presentation more fun, easier to understand and more visually memorable.

Bio-Logic Aqua® Research Water Life Science® is the inventor and manufacturer of Nature’s Tears® EyeMist®, the first all-natural, Trade Secret tissue culture grade pure water tear film mist to soothe dry eye symptoms without eye drops or formulated chemicals.

For more information, visit or call 1-800-FOR-MIST (367-6478).


Have you ever seen the DVD, The Human Tear Film—Mist Versus Eye Drops? If you have, what did you think of it? If you haven’t seen it, would you like to? Do you know someone who has seen the DVD? What do you think of new water research and new technology? Were you aware of the fact that you are always evaporating?

If you have comments or stories you’d like to share, why not get involved? We’d like very much to hear from you! You can reach us in the following ways. 800-367-6478 ~ Fax 541-474-2123 or on Twitter at @sharonkleynehr

Sharon Kleyne Talks About Tear Film

Water Life Science® Advocate Sharon Kleyne Offers Eye Education. Water Researcher Sharon Kleyne Explains Water in the Eye.

Sharon Kleyne, host of the nationally syndicated radio program, The Sharon Kleyne Hour Power of Water, Global Climate Change and Your Health on Voice of America, has battled dry eye disease for more than two decades. Her weapons of choice: new water technology, research and education. For the layman, Kleyne stresses education. “We can never know enough,” says Kleyne. “That’s why I am always in teaching mode.”

Sharon Kleyne, creator of a new Water Life Science® lifestyle whose water research and new water technology discoveries have earned her a global reputation as an expert on dry eye disease and supplementation of the eye’s and the body’s water vapor, knows that the scourge of dry eye disease begins with over-evaporation of the eye’s tear lens. “I want people to understand this,” Kleyne says, offering facts about the eye and its lens.

The primary function of the tear film, Sharon Kleyne explains, is to provide clear refractive properties to the ocular surface, and this air-water interface is the primary refractive structure of the eye. The tear film’s second function is to protect the epithelial surface by continually washing away the wide variety of debris and material that comes into contact with the ocular surface. Major invasive debris consists of dust, antigens and liquids. Since evaporation continues whenever the eye is open, tears must be constantly generated. When this process is interrupted or breaks down, Kleyne shows us, then dry eye disease attacks.

“The tear film itself is 99% water,” Sharon Kleyne says. “When the tear film dehydrates due to excessive water vapor evaporation, you feel the onslaught of redness, swelling, blurred vision, itchiness and headaches. Kleyne, founder of Bio-Logic Aqua® Research Water Life Science®, encourages everyone to use the only effective water-only supplement for dry eye disease on the international market. This product was created by Kleyne’s water research center where she discovered a new water technology that replenishes the compromised tear film of the eye with pure water and no chemicals or additives. ”Nature’s Tears® EyeMist® for dry, dehydrated eyes,” says Kleyne, “is the only Trade Secret tissue culture grade water in the world to supplement over-evaporation of the eye’s tear film and checkmate dry eye disease.”

Nature’s Tears® EyeMist® is applied to the eyes by a personal hand-held humidifying device emitting a pure, pH balanced, 100% water micron mist for dry eyes. The product is endorsed by more than 22,000 ophthalmologists and optometrists nationwide and was successfully test-marketed in more than 70,000 outlets.

For healthy eyes, Sharon Kleyne insists that people need to supplement the tear lens several times a day. Unfortunately, many unwittingly turn to saline solution eye drops for relief. Kleyne points out that saline drops can sting, and they can blur your vision. More important, saline eye drops do not supplement or replace water that has been lost from the tear film due to evaporation. Instead, saline eye drops trap water. They do nothing to replenish water, and without replenished water, the dry eye condition persists and eventually gets worse.

Sharon Kleyne Reveals The Truth about Dry Eye, Water and the Cornea

Corneal dry eye could begin with water loss from the eye’s tear film.

“Ocular dryness (dry eye) can deplete corneal stem cells.”

Ula Jurkunas, MD, Harvard Medical School, July 11, 2011

Sharon Kleyne, water and health advocate, Bio-Logic Aqua Research Founder, and host of the Sharon Kleyne Hour – Power of Water radio talk show. New educational dry eye discovery will motivate the public to become more proactive in taking better care of their eyes – and the importance of the function of water in the tear film. The importance of water in alleviating dry eye symptoms and maintaining corneal health was discussed during two on-air interviews by Sharon Kleyne, with Harvard Corneal Researcher Dr. Ula Jurkunas, a clinician scientist heading corneal research (July 11, 2011) and with Lasik pioneer Dr. Marguerite McDonald, a clinical Professor of Ophthalmology at NYU and refractive eye surgeon (June 1, 2009).

Nearly everyone experiences dry eye and eye dehydration symptoms, including infants. Dry eye caused by dry air and diet accounts for 80% of eye doctor visits in the United States. Dry eye can lead to blindness. Most people in the world do not take the condition of dry eye seriously.

Recent research at Harvard University and elsewhere, now provides a graphic picture of just what happens, physically, when the eye surface, especially the protective “tear film” covering the cornea (the clear part of the eye), begins to lose water, resulting in dry eye and dehydration symptoms.

Doctors Jurkunas and McDonald agreed with Mrs. Kleyne that loss of water in the tear film is the underlying cause of dry eye. According to Dr. Jurkunas, “It is important to keep the cornea clear and hydrated. When the tear film is too dry, the cornea becomes somewhat irritated and opaque.” According to Dr. McDonald, “When the tear film lacks sufficient water, small corneal ulcers can begin.” Chronic dry eye could cause loss of vision.

According to Dr. Jurkunas, “Corneal stem cells originate in the conjunctiva (the fleshy inner corner of the eye) and migrate across the white (sclera) to the corneal epithelium (the membrane covering the cornea).” Ocular dryness can cause stem cell deficiency.

Dr. Jurkunas explains that chronic dry eye, eye infections, allergies, and other conditions, can lead to a permanent impairment in the production of corneal stem cells. This is called “corneal stem cell disorder.”

Dr. McDonald reported that dry eye disease is a health crisis in the United States that can lead to severe eye discomfort, loss of work productivity, stress, fatigue, allergies, impaired vision, and, ultimately, blindness. Sharon Kleyne revealed research has discovered that dry eye and tear film dehydration can be caused by numerous environmental conditions, including dry air (low humidity), polluted air, improper diet, sugar, lack of sleep, climate change, wind, insulated walls and windows, forced air heating and cooling – and most importantly, not drinking enough pure, 100% water.

Both Dr. McDonald and Dr. Jurkunas agreed with Sharon Kleyne’s concerns about the global dry eye crisis and her assertion that “good hydration equals good vision.”

Listen to Sharon Kleyne Hour – Power of Water airs Mondays, 10 a.m., PST/PDT. The syndicated show is heard on Voice America/World Talk Radio, Green Talk Network and Apple iTunes. Go to for summaries and replays of past shows.

© 2011 Bio-Logic Aqua Research

Sight Preservation in Children around the World

Guest: Eugene Helveston, M.D., (Bloomington, IN), Professor Emeritus of Ophthalmology at Indiana University and a staff member of ORBIS International

This is a paraphrased summary of an interview on the Sharon Kleyne Hour – Power of Water Internet radio talk show on World Talk Radio, Apple iTunes and Green Talk Network. Sharon Kleyne is an internationally recognized entrepreneur, water and health advocate, and Founder of Bio-Logic Aqua Research and Save a Child’s Life Foundation. To hear the complete show, go to

Sharon Kleyn: Dr. Eugene Helveston is a retired Ophthalmology Professor at Indiana University Medical School. Since 2000, he has volunteered for ORBIS International, which conducts pediatric eye care screening, training and sight preservation programs in third world countries. Does ORBIS have programs in the US, Dr. Helveston?

Dr. Eugene Helveston: Only recruitment programs. We enlist eye care professionals to travel overseas to help reduce eye diseases such as dry eye and preventable blindness.

S: What is the status of eye care education and children’s sight preservation worldwide?

E: Most children are born with normal vision but immature eyes. Development takes place rapidly and naturally and parents usually don’t pay much attention. But things can go wrong very fast. Parents must be educated to detect eye health problems early, such as poor vision and dry eye.

S: What are the signals of good eyesight in newborns?

E: The cornea should be naturally clear, glistening and bright, with no mucus or mottled spots. The tear film should look normal, with no dry eye symptoms.

S: Explain about the tear film.

E: The tear film is the primary vehicle for moistening and light refraction and it maintains perfect eye clarity. It should contain sufficient natural water not look dry or mottled, which are symptoms of dry eye. Very few parents are aware of this.

S: What are other things to look for?

E: A white reflection appearing inside the eye, called a “cat’s eye.” This is the earliest sign of retinal blastoma and it infects one in 18,000 to 20,000 children. It not only causes blindness, it is lethal if not treated.

S: Are there dry eye or vision symptoms related to the skin around the eye?

E: Yes, especially in older children, toddlers and preschoolers. Parents should look for squinting and trouble seeing but may miss this because to the child, this is perfectly normal.

S: Yes, we interviewed Dr. Marguerite McDonald a few weeks ago, who said that she was nearly blind as a child but was able to compensate and it was two years before her parents noticed.

E: That’s common. I’ve often fitted children with glasses and had them tell me that they never noticed tree leaves before.

S: What should US parents look for?

E: Eyes should be symmetrical and moist, with no signs of dry eye or abnormality. They should focus within a few weeks and be able to follow a finger. The child should be aware of their environment. There should be no excessive tears, and no cataracts or tumors. Visual acuity should be checked fairly young.

S: Tell us more about ORBIS.

E: One-half of the world’s 160,000 ophthalmologists live in developed countries. The other half are in dire need of equipment, education and a more enlightened population. ORBIS has permanent staff in India, Viet Nam, Bangladesh, China and Ethiopia. We also operate the “Flying Eye Hospital,” a DC-10 airliner. In each country, we put together an educational and service sight preservation program to meet local needs needs.

S: What have you learned about eye care and dry eye China?

E: The natural incidence of nearsightedness in Chinese children is much higher than in the US – about 15%. This may be genetic, or it may be environmental or cultural.

S: Or it could be due to dry eye from dry air and extreme pollution. What do you do for ORBIS?

E: I set up standards of care, locate equipment, and select key doctors in target countries to train in modern sight preservation practice and diagnosis.

S: Is the US the most advanced country for eye care?

E: Without question.

S: Is increasing dry air and dry eye a factor in the third world countries?

E: It can be. In Nepal, for example, the elevation of many towns is over 10,000 feet, so air is naturally very dry and dry eye is common. Altitude and dry air can affect vision and accelerate childhood eye diseases.

S: One of my eye health recommendations is to drink sufficient natural water to prevent dry eye. Do you have any nutritional advice?

E: The majority of preventable blindness, which can be as much as 75% of all blindness, has to do with vitamin A deficiency. This is most common in sub-Saharan Africa, India and China.

S: What are some vitamin A foods?

E: Natural foods such as whole grain rice, fresh vegetables, whole wheat. Rubella vaccinations are also important. Folk remedies such as rubbing mud in the eyes should be avoided.


Bio-Logic Aqua Research – Rogue Media Division.
1-800-FOR-MIST (367-6478)

Dr. Robert Latkany, author of The Dry Eye Remedy

Guest: Robert Latkany, MD (New York, NY), Ophthalmologist and author, The Dry Eye Remedy (Hatherleigh Press 2007)

I was pleased to have dry eye pioneer Dr. Robert Latkany as a guest on the Sharon Kleyne Hour – Power of Water. Dr. Latkany is reportedly the only ophthalmologist specializing in dry eye disease and tear film hydration. He is author of the best selling book, The Dry Eye Remedy.

I became aware of Dr. Latkany after reading an article about his book and his New York City medical practice in the Wall Street Journal (“A Closer Look at Dry Eye” by Rhonda Rundle, May 1, 2007). Nature’s Tears EyeMist, an all-natural hand-held moisturizing mist for dry eye hydration, was mentioned. So naturally, I called him and we became allies in this important cause.

Dr. Latkany and I agree on the worldwide need for dry eye treatment alternatives, prevention and education. There is also an urgent need to address the plight of the thousands who go blind every day from dry eye disease, dry air and inadequate water and sanitation.

According to Dr. Latkany, dry eye disease and tear film dehydration are the #1 reason for US eye doctor (ophthalmologist) visits. The condition can become extremely serious, especially as we grow older. Since most people with dry eye disease don’t experience severe symptoms, it often goes undiagnosed. Primary symptoms of chronic dry eye include briefly blurred vision, fatigue, increased allergic sensitivity, burning eyes, red eye and frequent headaches.

Untreated chronic dry eye disease, according to Dr. Latkany, could result in loss of eyesight. Dry eye disease and tear film dehydration can cause cracking and scarring of the cornea, leading to infection and other eye diseases. Allergies can contribute to dry eye symptoms but so can the antihistamines commonly found in eye drops.

I asked Dr. Latkany about dry eye and computers, just as I asked Dr. Marguerite McDonald and Dr. Philip Paden. He said that people who spend all day at the computer often blink far less frequently. As a result, more tear film water (moisture) evaporates and the “blink muscles” weaken.

I discussed my own research with Dr. Latkany, previously shared on the Sharon Kleyne Hour. Many dry air factors cause dry eye, red eye, burning eyes and tear film dehydration. Dry air indoors is a major cause of dry eye, especially dry air from forced-air heating and cooling, and man made household chemicals can cause dry eye. I suggest all-natural alternatives such as a mist humidifier or air purifier, or simply setting out bowls of water or opening a window (unless the air outside is extremely dry or polluted).

I observed that people take daily care of their teeth, hair and skin and wondered why they take eye hydration for granted. Dr. Latkany believes the name “dry eye” just doesn’t sound like a disease. As for treatment alternatives, Dr. Latkany advises all-natural alternatives over dye drops, such as drinking lots of water, exercising regularly, taking care of your health and hydration and above all, educating yourself about dry eye and eye care treatment alternatives. We also discussed the importance of Nature’s Tears EyeMist and eye misting and moisturizing in general for dry eye, red eye and burning eyes, as reported in the Wall Street Journal article.

Dr. Marguerite McDonald on Dry Eye Causes and Treatment

Dry Eye, Dry Air and Dehydration Disease

Guest: Marguerite McDonald, MD, (Long Island, NY), Lasik pioneer, Ophthalmologist and dry eye consultant.

Dr. Marguerite McDonald

(Reference: McDonald, M, MD, “The Forgotten Symptom: Dry Eye in Cataract Patients,” Ophthalmology Times, October 1, 2008)

Dry eye and tear film moisture loss are early symptoms of dry air, global drying and dehydration disease. Untreated dry eye can cause corneal ulceration and scarring, eye allergies, eye inflammation, numerous eye diseases and blindness. Because The Sharon Kleyne Hour Power of Water, on World Talk Radio, is devoted to the study of dry air, dehydration diseases and health as part of the power of water; dry eye is a frequent topic. Dry eye guest experts have included Dr. Marguerite McDonald, Dr. Philip Paden, Dr. Robert Latkany, Dr. Ilene Gipson and others.

Continue reading “Dr. Marguerite McDonald on Dry Eye Causes and Treatment”